Naslov (srp)

Analiza i upoređenje kvaliteta života bolesnika sa nemetastatskim karcinomom prostate koji su lečeni radikalnom prostatektomijom i hormonoterapijom

Autor

Dinić, Ljubomir, 1972-

Doprinosi

Bašić, Dragoslav, 1967-
Ignjatović, Ivan, 1964-
Aleksić, Predrag, 1963-
Đorđević, Nebojša, 1955-
Veljković, Andrej, 1980-

Opis (srp)

The aim of the study was to evaluate health-related quality of life inpatients with non-metastatic prostate cancer. The patients were divided intwo groups. The first group consisted of patients who underwent RRP, andthe second group consisted of those who were primarily treated withhormonal therapy for 12 months and then underwent external radiationtherapy (H + Z). The (EPIC) questionnaire was used to evaluate healthrelatedquality of life (HRQoL), the (IIEF-SF) questionnaire was used toassess erectile function, the (ICIQ-UI) questionnaire was used to assessurinary incontinence, and IPSS questionnaire was used to assess lowerurinary tract symptoms. All patients filled out questionnaires before thestart of treatment, in the 3rd, 6th, 12th, 15th, 18th and 24th months of followup.At 12-month follow-up compared to baseline, the greatest decrease inmean IIEF score (p < 0.05), the greatest increase in mean ICIQ-UI score(p < 0.01), the greatest decrease in the mean IPSS score (p < 0.001), andthe greatest decrease in IPSS QoL score (p < 0.001) was in RRP group. ForHRQoL, according to the EPIC results, urinary function, urinaryincontinence and sexual function significantly decreased compared tobaseline after 12 months (p < 0.05 for all) in RRP group, and hormonalfunction, sexual function and sexual bother (p < 0.001 for all) in the (H +Z) group. From 12th to 24th months in the RRP group, there were nochanges in the mean IIEF, ICIQ-UI, IPSS, IPSS QoL scores compared tothe 12th month, nor in the HRQoL results. In the H + Z group, a significantdecrease in the IIEF score, a decrease in sexual function and sexual bother,and an increase in hormonal function were verified. From a HRQoLperspective, both treatment modalities can offer satisfactory functionaloutcomes. RRP has the greatest impact on urinary and sexual function,hormonal therapy on sexual and hormonal function, and H + Z on sexualfunction and sexual bother.

Opis (srp)

Biografija autora: list. 178,Bibliografija: list. 137-165 Datum odbrane: 12.01.2023 Urology

Jezik

srpski

Datum

2022

Licenca

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