Naslov (srp)

Skalabilna softverska platforma za pretraživanje hemijskih i bioloških repozitorijuma

Autor

Arsić, Branko J. 1984-

Doprinosi

Milentijević, Ivan 1965-
Rančić, Dejan
Stoimenov, Leonid
Tošić, Milorad
Bašić, Milan

Opis (eng)

This dissertation is about the SpecINT (Spectral Integration), a scalable software platform, which benefits from the Semantic Web and from the results of spectral graph theory for data integration and exploring semanticbased repositories. In order to save time and resources, institutions are in need of a comprehensive overview of relevant and most recently published data globally. According to statistics, only one substance out of thousands satisfies the preclinical and clinical tests’ criteria and can be used as a medicament. Laboratory conditions require a lot of time and resources to test the effect of large number of substances, and that is why application of in silico models is found necessary. The methodology applied to achieve this goal is based on the coordinates of graph eigenvectors used for automatic join of sub-queries in Federated SPARQL query out of which only the most relevant data sources within repositories are taken into consideration. Such an approach enables reduction of number of duplicates in the results obtained, but also provides useful results for the researchers. In this way the integration of repositories can be effected without a common ontology between them, leaving an impression there exists a searchable central and virtual storage. The platform is developed in collaboration with the Laboratory for Cell and Molecular Biology of the Faculty of Science, University of Kragujevac. However, the methodology can be applied more broadly, since it is based on the „Open Data” standards and concepts.

Opis (srp)

Bibliografija: str. 138-139. Datum odbrane: 12.10.2020. Semantic Web

Jezik

srpski

Datum

2020

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY-NC 2.0 AT - Creative Commons Autorstvo - Nekomercijalno 2.0 Austria License.

http://creativecommons.org/licenses/by-nc/2.0/at/legalcode